Categories
EndoRE PAD remote endarterectromy

Should the SFA be revascularized during an inflow procedure?

Sketches - 12

The patient is a 70 year old man who arrived with complaints of worsening claudication, worse on the left leg. He smokes over a pack a day. On exam, he only had femoral pulses, nothing was palpable below. PVR showed multilevel disease with an ABI of 0.42 on the left leg.

PVR preop

CTA was done showing that both his SFA and PFA were occluded, along with occlusion of his AT in the mid leg, and tibioperoneal trunk.

cta TIBIAL_1

There is a reconstitution point on the PFA, and there is also SFA constitution. Looking at this, it was apparent to me that it would be possible to endarterectomize the whole of the iliofemoral and femoropopliteal system from a single groin incision, but the question being, would a profundaplasty be sufficient.

Arrow points to calcium free terminus for SFA EndoRE
Arrow points to calcium free terminus for SFA EndoRE

The textbook answer is profundaplasty, but given my experience with endarterectomy, it has become apparent that removing all the plaque, including CFA and iliofemoral plaque reduces the chance that clamp injury and stenosis occur, and that placed in the common iliac system have better patency than those placed in the external iliac, particularly crossing the inguinal ligament into a patch.

The other observation is that with this exposure, SFA remote endarterectomy is very simple to do, but becomes more difficult in a redo situation. The only problem with going ahead with it is that the runoff is poor -all three tibial vessels occlude, but a very robust posterior tibial artery reconstitutes proximally from well developed collaterals.

The CFA, PFA, and SFA were exposed as shown in my sketch at the beginning of the post. Wire access up and over from the right side allowed for secure control of the aortoiliac segment. The endarterectomy was started from the PFA reconstitution point and the CFA plaque was mobilized. The SFA plaque was transected in a proximal arteriotomy and the plaque was mobilized with a ring to its origin. The CFA plaque then was mobilized with the ring dissector over a wire (for security in case of rupture), up to the EIA origin and cut.

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The distal SFA plaque was endarterectomized to the planned end point above the knee joint.

Image-4

The specimen is shown below.

specimen

The arteriotomies were repaired with patches. The common iliac artery was stented to improve the flow. The SFA end point was managed with a stent, placed proximal to the first large geniculate collateral.

prepost sfa endpoint

Completion angiograms show widely patent EIA, CFA, PFA, and SFA

Completion

The patient recovered and was discharged on POD#3. His postop ABI’s are shown below.

ABI post2

They are improved compared to preop, with ABI’s of 0.65. Notably, he did have a weakly palpable posterior tibial artery pulse, and multiphasic signals in all three tibial vessels. While I don’t know if the SFA revascularization will stay open, I am confident the PFA will, and this will keep him from his symptoms recurring and is a durable procedure.

Ideally, if he had needed a distal revascularization, a vein bypass would be the answer, but in the setting of inadequate conduit, it is very simple to endarterectomize from the below knee popliteal artery the remaining plaque and either patch to the patent tibioperoneal trunk or perform a short POP to posterior tibial artery bypass. He did not require this.

I don’t know the answer to the titular question, but in the setting of an inflow procedure, the best chance at opening the SFA is during the inflow procedure because of the exposure, and it is very simple to do when the lesion is minimally calcified.

Categories
EndoRE PAD remote endarterectromy techniques

Removing Occluded Stents For Critical Limb Ischemia

Image-22

The patient severe claudication and nocturnal rest pain and had undergone an inflow procedure at another hospital consisting of a common femoral endarterectomy and a single stent to the external iliac artery near its origin from the iliac bifurcation. He also had undergone a concurrent SFA atherectomy which closed and was treated with SFA stents extending from the SFA origin to the above knee popliteal artery. Unfortunately, his rest pain worsened.

ABI2

On exam, he had a femoral pulse only and no distal pulses, only monophonic and weak pedal signals. The right groin wound had been treated for postoperative wound infection and there was still some swelling and a stitch abscess, but no deep infection. CTA showed that his profunda femoral artery had a focal dissection or stenosis at the origin along with overhang of his SFA stents across the origin of the PFA. The SFA stents were occluded along their whole length. There was remnant disease of the external iliac artery as well.

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There was reconstitution of a diseased but patent above knee popliteal artery with three vessel runoff. He had had harvest of his greater saphenous vein. Treatment options included multisegment arm vein with redo profundaplasty, but given the inflammation around his recently operated, recently infected groin, I was concerned for wound infection. He was also quite disabled by his worsened pain. The other option was to access the left common femoral artery and placed a sheath up and over and wire across the diseased profunda and intervene on it, but with the stent in place, I would have to place likely another stent across the origin. I could then attempt a bypass with arm vein or prosthetic graft using this compromised artery as inflow for a bypass to the below knee popliteal artery or a tibial vessel but I doubted this would be durable, nor resistant to infection if prosthetic was used.

Remote endarterectomy (EndoRE) gave me a third option. It is a hybrid technique, but based on an old and established technique of open remote endarterectomy dating from the 60’s. Rings (Vollmer Rings, LeMaitre Vascular) are used to dissect occlusive plaque under fluoroscopy, and a cutting ring (Moll Ring Cutter, LeMaitre Vascular) is used to cut the plaque at the chosen location. Because the distal end point of dissection is not surgically exposed, but rather fluoroscopically guided, it is termed Remote Endarterectomy. Wire skills are required to access and repair any dissections that may occur.

I have presented in the past a series of cases where I removed occluded stents. Because the dissection is carried out outside the plaque, it is also outside the stent. Retrograde EndoRE of SFA plaque can be carried out up to the SFA origin, and avoid a groin incision which in this case was important. Therefore, a proximal thigh exposure of the SFA and EndoRE was planned with endovascular access by left CFA as described.

Photo Apr 15, 10 08 52 AM

The SFA was a hard, calcified pipe and control was achieved with vessel loops which allow passage of the ring and occlusion of the artery once the plaque and stents were removed. The artery was opened via longitudinal arrteriotomy and the plaque mobilized and divided. The proximal SFA plaque was then dissected (above and below).

proximal dissection

There was immediate establishment of a robust pulse in the proximal SFA after removal of the plaque.

Photo Apr 15, 10 14 06 AM

Distally, the plaque would not mobilize at a point in the artery where there was laxity in the artery and especially adherent plaque and therefore, the distal SFA was cut down on to reaccess the stent from below.

Cutdown to reaccess plaque, basically a reversion to the original pre-endovascular technique.
Cutdown to reaccess plaque, basically a reversion to the original pre-endovascular technique.
Mobilizing stent from above and below
Mobilizing stent from above and below
The distal plaque was cut with a Moll Ring Cutter. The removed specimen in total is below.Photo Apr 15, 12 03 16 PM

The arteriotomies were repaired with patch angioplasties using bovine pericardium. This allowed for completing the procedure with endovascular techniques which included the distal end point dissection, profunda stenosis, and external iliac stenosis.

Distal end point managed with self expanding stent.
Distal end point managed with self expanding stent.
PFA

EIA

At completion, there was a palpable dorsalis pedis artery pulse. The composite angio with preop CTA centerline reconstruction are shown below.

completion

He had relief of his symptoms. Prior to discharge, ABI and PVR’s show normalization of flow to his foot.

Image-2

Conclusion: In my experience, the longevity of these lesions is dependent on the same factors dictating other revascularizations -excellence of inflow, optimization of profunda outflow, and good tibial outflow. The conduit, being the recanalized original artery, is not as good as a single vein, but it remodels and becomes normal artery based on micro pathology. Failure occurs at the stent with the usual restenosis that can occur in some but not all people, and in isolated points in the artery where likely remnant tissues scar creating focal lesions. Frequent surveillance achieves acceptable primary and secondary patencies. Thromboses do occur. Unlike PTFE grafts, thromboses in EndoRE is usually limited to the recanalized artery without distal embolization. Stent removal is challenging but feasible. In this patient, a second cut down was required to achieve plaque and stent removal. The groin was not re-entered, avoiding dissection in a recently infected, surgical wound. If the popliteal was occluded, a popliteal endarterectomy via a below knee cutdown is possible achieving total femoropopliteal plaque clearance, and the below knee popliteal artery can then be used for a very short bypass to one of the tibial arteries if indicated and if autologous vein is limited in availability.

EndoRE offers a third option after bypass and intervention and should be in a vascular surgeon’s armamentarium.

Categories
Journal Club SVC

April Journal Club

April Journal Club is coming up on us this Tuesday, April 21, and will be centered around SVC Syndrome and central venous occlusive disease. Dr. XY Teng won the award for best presentation in the March Club meeting. Our presenters this Tuesday are:

Dr. M. Abbasi – Aldoss et al link

Dr. D. Hardy – Gwon et al link

Dr. L. Rangel – Bakken et al link

Same rules apply. See you there.

Categories
bypass PAD techniques Wounds

Deep rescue from a hospice: saving a patient from hip disarticulation with advanced hybrid inflow procedure and vein bypasses

PREOP.001

The patient is an elderly man who had bilateral above knee amputations after failure of aortobifemoral bypass grafts at an outside institution. Unfortunately, he had no femoral pulses and his amputation on the right broke down (image above). His left stump had erosion of his femur to the skin with rest pain as well, but was at least covered by skin for now. He was declared too sick for hip disarticulations and was sent to a hospice where he failed to pass away. After a year there, he was sent to us for an evaluation.

He was suffering from rest pain and had complete breakdown of the skin over his amputation stump. More worrisome was the development of gangrenous scrotal and decubitus ulcers which were small but persistent and also foci of pain. CTA showed the following:

PREOP CTA.001

The aorta was occluded below his renal arteries. An AV fistula near his common femoral vein lit up his right iliac vein on the CT above. He had had a prior aortobifemoral bypass but this was occluded. Gratifyingly, it was anastomosed proximally end to side, giving us options. As with any revascularization, we had an inflow source -his aorta, and several potential outflow sources (CTA below, contrast filling iliac vein from AVF’s).

OUTFLOW.001

In particular, his distal profunda femoral artery showed promise. Vein mapping revealed a short segment of basilic vein in his arm to use as bypass, but we needed inflow from the aorta.

I have come to appreciate two things about aortoiliac recanalization. First is that passing the wire antegrade is far likelier to stay in the true lumen at least in the aortic inflow segment -retrograde wire passage inevitably dissects the occlusive aortic plaque and reentry into the true lumen of the diseased aorta is just as challenging as in the leg. The second is vein bypasses have excellent patency in challenging conditions -you just need excellent inflow and an arterial bed to perfuse.

My plan was to cross the aortoiliac occlusion with a wire from the left arm. Once the right iliac system was entered, it didn’t matter if I was in a subintimal plane. The wire could be seated in the common femoral artery to access with a surgical exposure. Once this was done, my intention was to perform remote endarterectomy of the external iliac artery and stent from the aorta to the common iliac artery. The endarterectomized external iliac artery would be the inflow source of a later staged ilio-cross femoral bypass to revascularize his left AKA stump. The common femoral artery at its origin would provide inflow to a short vein bypass to his profound femoral artery.

The wire passed readily into the right iliofemoral system and a groin exposure and common femoral arteriotomy allowed me to retrieve the wire which had been passed from the left arm. A remote endarterectomy was performed over the wire which I do to ensure access in case the artery ruptures (specimen below).

OR IMAGES.001

This allowed me to place a sheath into the right iliac system in the now reopened external iliac artery. Balloon angioplasty of the aortoiliac segment created working space for placement of balloon expandable stents from the infrarenal aorta to the common iliac artery, restoring an excellent pulse in the right groin.

The profunda femoral artery was encased in scar tissue, but following the occluded PFA from the CFA, I was able to expose an open segment and cut it open in the scar tissue. There was back bleeding, and I controlled the artery by placing a small Argyll shunt into the artery and reperfusing it from the recanalized right iliac system.

OR IMAGES.002

The Doppler flow in the shunt was excellent, suggesting great outflow potential. The bypass was performed over the shunt with reversed basilic vein. Completion arteriography showed excellent flow.

PLANNING SLIDE.001

The amputation stump was debrided of dead bone and muscle and the graft was covered with a sartorius muscle flap.

OR IMAGES.003

Before and after images are shown. The remaining open wound granulated well, and ultimately accepted a split thickness skin graft. His scrotal and decubitus ulcers healed as well (below at 6 months post op).

IMG_2380

His left AK stump subsequently degraded while he recovered so three months after this operation, he underwent a right external iliac to left profunda femoral artery bypass with cadaveric vein.

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I don’t like using cadaveric vein, but we really had no options. The right external iliac artery was approached through a right lower quadrant (transplant) incision and a punch biopsy of the artery revealed only normal adventitia on pathology. The EIA was soft and sewed well -essentially a normal artery brought back from the dead. The left profunda femoral artery was large after endarterctomizing its origin and accepted the bypass flow well.

The mortality from hip disarticulation in the setting of gangrene and infection is very high, and I feel that standard approaches to this problem -prosthetic axillo femoral bypasses, thoracobi-femoral bypasses, in the setting of advanced infection and gangrene were unlikely to succeed. In over 1.5 years of followup, everything has remained patent, and the patient lives independently.